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- Title
A New Sterol From the Polypore Fungus Ganoderma luteomarginatum and Its Cytotoxic Activities.
- Authors
Htoo, Zin Paing; Kodama, Takeshi; Win, Nwet Nwet; Ikumi, Naotaka; Shiokawa, Ken-ichi; Morita, Hiroyuki
- Abstract
A new sterol, ganolutol A (1), together with 4 known compounds 2 to 5, were isolated from the polypore fungus Ganoderma luteomarginatum collected in Myanmar. The chemical structures of the isolated compounds were determined based on extensive spectroscopic analyses in conjunction with comparisons with published data. Compounds 1 to 4 exhibited moderate cytotoxic activities against A549 (lung), MCF-7 (breast), and HeLa (cervical) human cancer cell lines, with IC50 values ranging from 10.1 to 86.6 μM.
- Subjects
MYANMAR; GANODERMA; BREAST; FUNGI; LUNGS; CHEMICAL structure; CELL lines; CANCER cells
- Publication
Natural Product Communications, 2022, Vol 17, Issue 5, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X221098852