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- Title
Toxocara canis Larval Migration Causing Verminous Pneumonia in Fading Puppies From 2 Scottish Terrier Litters.
- Authors
Buckle, Kelly N.; Hardcastle, Michael R.; Scott, Ian; Craig, Linden E.; French, Adrienne; Gedye, Kristene; Collett, Mark Grey
- Abstract
Migration of vertically transmitted Toxocara canis larvae through the liver and lungs is poorly documented as a cause of periparturient mortality in puppies. This case series describes 4 cases of fading puppies in 2 litters from 2 different bitches owned by the same breeder. Of the 4 cases, 4 had verminous pneumonia, 2 had fibrinoid necrosis of pulmonary arterioles, 4 had hepatic necrosis and inflammation, 2 had hepatic thrombophlebitis, and 1 had tracheal occlusion. These lesions were associated with migrating nematode larvae morphologically consistent with T. canis. The identity of the larvae was confirmed by sequencing of a portion of the ITS-2 region of nuclear ribosomal DNA. The tissues involved are consistent with the known migration pathways of this parasite. The dam of the first litter was negative for Toxocara spp. and other intestinal parasites by fecal floatation. This report highlights the need to consider T. canis migration in the differential diagnosis of fading puppies.
- Subjects
TOXOCARA; PUPPIES; INTESTINAL parasites; RIBOSOMAL DNA; NUCLEAR DNA; CHLOROPLAST DNA
- Publication
Veterinary Pathology, 2019, Vol 56, Issue 6, p903
- ISSN
0300-9858
- Publication type
Article
- DOI
10.1177/0300985819852131