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- Title
Streamlined One-Pot Synthesis of Nitro Fatty Acids.
- Authors
Hassan, Mohamed; Krieg, Sara-Cathrin; Nde, Cedric Ndefo; Roos, Jessica; Maier, Thorsten J.; El Rady, Eman A.; Raslan, Mohamed A.; Sadek, Kamal U.; Manolikakes, Georg
- Abstract
A novel method for the synthesis of nitro fatty acids (NFAs), an intriguing class of endogenously occurring lipid mediators, is reported. This one-pot procedure enables the controlled and stereoselective construction of nitro fatty acids from a simple set of common building blocks in a highly facile manner. Thereby, this methodology offers a streamlined, highly modular access to naturally occurring nitro fatty acids as well as nonnatural NFA derivatives.
- Subjects
FATTY acids; NITROALDOL reactions; PHARMACEUTICAL chemistry
- Publication
European Journal of Organic Chemistry, 2021, Vol 2021, Issue 15, p2239
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.202100247