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- Title
Dendrimers for ocular drug delivery.
- Authors
Lancina, Michael G.; Yang, Hu
- Abstract
Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique, highly organized branching structure. In recent years, promising results using dendrimer vehicles to deliver ocular drugs through different routes of administration have been reported. In this minireview, we briefly summarize these results with emphasis on the dendrimer modifications used to target different ocular structures.
- Subjects
DENDRIMERS; OPHTHALMOLOGICAL therapeutics; NANOMEDICINE; DRUG administration; NANOPARTICLES
- Publication
Canadian Journal of Chemistry, 2017, Vol 95, Issue 9, p897
- ISSN
0008-4042
- Publication type
Article
- DOI
10.1139/cjc-2017-0193