We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Concomitant Epstein-Barr Virus-Negative Large B-Cell Lymphoma (Richter Syndrome) and Epstein-Barr Virus-Positive B-Cell Lymphoproliferation After Treatment With Fludarabine and Cyclophosphamide in a Patient With B-Cell Chronic Lymphocytic Leukemia.
- Authors
Compérat, Eva; Delmer, Alain; le Tourneau, Agnes; Molina, Thierry J.; Diebold, Jacques; Audouin, Josée
- Abstract
We report the case of a patient treated with a combination of fludarabine and cyclophosphamide after suffering from B-cell chronic lymphocytic leukemia for 10 years. Three months after treatment, the patient presented with an unusual association, not previously reported in the literature: Richter syndrome (monotypic Epstein-Barr virus-negative large B-cell lymphoma) with the proliferation of Epstein-Barr virus-positive B cells secreting a polytypic immunoglobulin A. The Epstein-Barr virus-positive lymphoproliferation can be accounted for by the type of immunosuppression induced by the treatment.
- Subjects
EPSTEIN-Barr virus; HERPESVIRUSES; ONCOGENIC DNA viruses; LYMPHOCYTIC leukemia; CHRONIC diseases; CHRONIC lymphocytic leukemia
- Publication
Archives of Pathology & Laboratory Medicine, 2006, Vol 130, Issue 8, p1227
- ISSN
0003-9985
- Publication type
Article
- DOI
10.5858/2006-130-1227-cevlbl