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- Title
Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time.
- Authors
Hanedan, Muhammet Onur; Yürük, Mehmet Ali; Arslan, Ali Kemal; Kılıç, Aşkın; Sayar, Ufuk; Mataracı, İlker
- Abstract
Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline®, Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany). Results: Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumincoated group than in the non-coated group (355.64±34.12 vs. 560.38±90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparinalbumin- coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion. Conclusion: Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course.
- Subjects
GERMANY; CARDIOPULMONARY bypass; RED blood cell transfusion; INTENSIVE care units; CARDIAC surgery; HOSPITAL mortality; OPERATIVE surgery
- Publication
Brazilian Journal of Cardiovascular Surgery, 2020, Vol 35, Issue 6, p913
- ISSN
0102-7638
- Publication type
Article
- DOI
10.21470/1678-9741-2019-0387