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- Title
Primary diffuse leptomeningeal primitive neuroectodermal tumor presenting as chronic meningitis.
- Authors
Koshy, K; Kulkarni, G; Nandeesh, B; Taalapalli, A
- Abstract
Primary diffuse leptomeningeal primitive neuroectodermal tumor is a rare meningeal neoplasm which can masquerade as chronic meningitis. While the clinical presentation and radiological features may provide a clue to this condition, meningeal biopsy is essential to clinch the diagnosis. A high index of suspicion and a low threshold for re-evaluating cases of neuroinfection that do not respond to empirical therapy are essential in this scenario. We present the case of a nine year old boy who was initiated on antituberculous treatment for chronic meningitis with hydrocephalus. Meningeal biopsy revealed a primary diffuse leptomeningeal primitive neuroectodermal tumor.
- Subjects
MENINGITIS treatment; MENINGITIS diagnosis; CHRONIC disease diagnosis; BIOPSY; DIFFERENTIAL diagnosis; HEADACHE; MENINGITIS; COMPUTED tomography; NEUROECTODERMAL tumors; MAGNETIC resonance imaging; CRYPTOCOCCUS neoformans; MENINGEAL cancer; CHEMORADIOTHERAPY; PANCYTOPENIA; ANTITUBERCULAR agents; SEIZURES (Medicine); SEPSIS; NAUSEA; CEREBROSPINAL fluid shunts
- Publication
Journal of Postgraduate Medicine, 2024, Vol 70, Issue 1, p46
- ISSN
0022-3859
- Publication type
Article
- DOI
10.4103/jpgm.jpgm_495_22