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- Title
Genomic Responses to Abnormal Gene Dosage: The X Chromosome Improved on a Common Strategy.
- Authors
Xinxian Deng; Disteche, Christine M.
- Abstract
The article discusses research on the gene expression of Drosophila cells with extra or missing copies of genes or chromosomes that are typical of cancers. It stresses that extra or missing copies of genes or chromosomes result in an imbalance that can lead to cancers, miscarriages, and disease susceptibility. It highlights how important gene expression balance is for cell function.
- Subjects
GENE expression; DROSOPHILA; GENETIC regulation; GENETICS; X chromosome; DISEASE susceptibility; CELL physiology; GENOMICS
- Publication
PLoS Biology, 2010, Vol 8, Issue 2, p1
- ISSN
1544-9173
- Publication type
Article
- DOI
10.1371/journal.pbio.1000318