We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Digital droplet PCR at the time of TKI discontinuation in chronic-phase chronic myeloid leukemia patients is predictive of treatment-free remission outcome.
- Authors
Colafigli, Gioia; Scalzulli, Emilia; Porrazzo, Marika; Diverio, Daniela; Loglisci, Maria Giovanna; Latagliata, Roberto; Guarini, Anna; Foà, Robin; Breccia, Massimo
- Abstract
In the setting of ddPCR-negative patients, comparison between ddPCR and RQ-PCR in prospective longitudinal monitoring after discontinuation showed that the results obtained by ddPCR anticipated the relapse by 3 months. Of these, 10 patients who had obtained a MR4.5 were followed with both methods: Of 10 patients who lost MR4, four were found positive by ddPCR 3 months earlier than by RQ-PCR.
- Subjects
CHRONIC myeloid leukemia; REVERSE transcriptase polymerase chain reaction
- Publication
Hematological Oncology, 2019, Vol 37, Issue 5, p652
- ISSN
0278-0232
- Publication type
letter
- DOI
10.1002/hon.2650