Found: 34
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Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 557, doi. 10.1007/s00204-018-2152-9
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- Publication type:
- Article
Highlight report: ‘Big data in the 3R’s: outlook and recommendations’, a roundtable summary.
- Published in:
- 2018
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- Publication type:
- Editorial
Protective effect of cadmium-induced autophagy in rat renal mesangial cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 619, doi. 10.1007/s00204-017-2103-x
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- Publication type:
- Article
A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 935, doi. 10.1007/s00204-017-2102-y
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- Publication type:
- Article
Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 921, doi. 10.1007/s00204-017-2109-4
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- Publication type:
- Article
Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 745, doi. 10.1007/s00204-017-2101-z
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- Publication type:
- Article
PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 705, doi. 10.1007/s00204-017-2077-8
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- Publication type:
- Article
Hepatotoxic combination effects of three azole fungicides in a broad dose range.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 859, doi. 10.1007/s00204-017-2087-6
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- Publication type:
- Article
Determining a threshold sub-acute dose leading to minimal physiological alterations following prolonged exposure to the nerve agent VX in rats.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 873, doi. 10.1007/s00204-017-2108-5
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- Publication type:
- Article
Linking site-specific loss of histone acetylation to repression of gene expression by the mycotoxin ochratoxin A.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 995, doi. 10.1007/s00204-017-2107-6
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- Publication type:
- Article
Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 633, doi. 10.1007/s00204-017-2106-7
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- Publication type:
- Article
Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 967, doi. 10.1007/s00204-017-2099-2
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- Publication type:
- Article
Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 907, doi. 10.1007/s00204-017-2096-5
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- Publication type:
- Article
Respiratory sensitization: toxicological point of view on the available assays.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 803, doi. 10.1007/s00204-017-2088-5
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- Publication type:
- Article
Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-d-glucuronide-induced cholestasis in rats.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 729, doi. 10.1007/s00204-017-2098-3
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- Publication type:
- Article
Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 611, doi. 10.1007/s00204-017-2097-4
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- Publication type:
- Article
GABA<sub>A</sub> receptor subtype selectivity of the proconvulsant rodenticide TETS.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 833, doi. 10.1007/s00204-017-2089-4
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- Publication type:
- Article
Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 777, doi. 10.1007/s00204-017-2092-9
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- Publication type:
- Article
The effects of the obesogen tributyltin on the metabolism of Sertoli cells cultured ex vivo.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 601, doi. 10.1007/s00204-017-2091-x
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- Publication type:
- Article
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 845, doi. 10.1007/s00204-017-2090-y
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- Publication type:
- Article
ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 717, doi. 10.1007/s00204-017-2084-9
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- Publication type:
- Article
Intestinal toxicity of deoxynivalenol is limited by <italic>Lactobacillus rhamnosus</italic> RC007 in pig jejunum explants.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 983, doi. 10.1007/s00204-017-2083-x
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- Publication type:
- Article
Arylamine <italic>N</italic>-acetyltransferase 1 in situ <italic>N</italic>-acetylation on CD3+ peripheral blood mononuclear cells correlate with NATb mRNA and NAT1 haplotype.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 661, doi. 10.1007/s00204-017-2082-y
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- Publication type:
- Article
Effects of arsenolipids on in vitro blood-brain barrier model.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 823, doi. 10.1007/s00204-017-2085-8
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- Publication type:
- Article
Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 953, doi. 10.1007/s00204-017-2080-0
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- Publication type:
- Article
Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 893, doi. 10.1007/s00204-017-2079-6
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- Publication type:
- Article
Toxicokinetic of tris(2-butoxyethyl) phosphate (TBOEP) in humans following single oral administration.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 651, doi. 10.1007/s00204-017-2078-7
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- Publication type:
- Article
Roles of cytosolic phospholipase A<sub>2</sub>α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-<italic>p</italic>-dioxin-exposed mice.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 789, doi. 10.1007/s00204-017-2081-z
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- Publication type:
- Article
Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 693, doi. 10.1007/s00204-017-2074-y
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- Publication type:
- Article
Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 669, doi. 10.1007/s00204-017-2073-z
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- Publication type:
- Article
Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 571, doi. 10.1007/s00204-017-2068-9
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- Publication type:
- Article
Predicting in vivo effect levels for repeat-dose systemic toxicity using chemical, biological, kinetic and study covariates.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 587, doi. 10.1007/s00204-017-2067-x
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- Publication type:
- Article
P21<sup>Waf1/Cip1</sup> depletion promotes dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells by inhibiting the Nrf2/HO-1 pathway.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 679, doi. 10.1007/s00204-017-2070-2
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- Publication type:
- Article
<italic>t</italic>-BuOOH induces ferroptosis in human and murine cell lines.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 2, p. 759, doi. 10.1007/s00204-017-2066-y
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- Publication type:
- Article