We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
HER-2 Oncogene Is Not Amplified in Primary Carcinoma of the Fallopian Tube.
- Authors
Stühlinger, M.; Rosen, A.C.; Dobianer, K.; Hruza, C.; Helmer, H.; Kein, M.; Koukal, T.; Reiner, A.; Klein, M.
- Abstract
73 women suffering from primary carcinoma of the fallopian tube underwent surgical excision of their tubes. The tissue was embedded in paraffin and investigated for HER-2 oncogene amplification with a quantitative polymerase chain reaction method. DNA could be extracted and successfully prepared in 65/73 samples. None of the tissue samples exhibited amplified the HER-2 oncogene. Data suggest that the HER-2 oncogene does not play a role in tumor transformation and progression in fallopian tube carcinomas. This contrasts with observations in ovarian carcinomas, with which fallopian tube carcinomas share many clinical, histological and biochemical similarities. Copyright © 1995 S. Karger AG, Basel
- Publication
Oncology, 1995, Vol 52, Issue 5, p397
- ISSN
0030-2414
- Publication type
Article
- DOI
10.1159/000227496