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- Title
TTA-RAPID WITH GOLD-NANOPARTICLE BIOMATERIAL TO TREAT CRANIAL CRUCIATE LIGAMENT DISEASE IN A JUVENILE DOG: A CASE REPORT.
- Authors
Ardelean, Alina Ioana; Ober, Ciprian; Dreancă, Alexandra; Dragomir, Mădălina Florina; Purdoiu, Robert; Magyari, Klara; Oana, Liviu
- Abstract
Introduction: Biomaterials based on bioactive glass with gold nanoparticles composites have applications in tissue engineering due to their cellular regeneration and angiogenesis capacities (Magyari et al., 2017). Tibial tuberosity advancement (TTA) Rapid is a new and accepted alternative to treat cranial cruciate ligament disease (CCL) in dogs (Samoy et al., 2015, McCartney et al., 2019). Anyway, complications are still present despite excellent long-term results (Samoy et al., 2015). Aims: The purpose of this study was to evaluate the effect of a gold-nanoparticle biomateral to enhance bone healing in order top prevent postoperative complications after TTA Rapid procedure. Materials and Methods: An 11-months-year-old Kangal was presented with CCL rupture, second degree patellar luxation and moderate stifle osteoarthritis. A previous surgical correction for patellar luxation was unsuccessful. During TTA Rapid fixation, lateralization of the tibial tuberosity was performed in order to correct patellar luxation. A glass-polimer-gold-nanopaticle composite was added in the osteotomy defect in order to accelerate bone healing. Results: Clinical and radiological follow-up was performed 30-days after surgery. The dog had excellent clinical outcome and complete bone healing. The TTA-Rapid gap was filled with bone and no progression of the osteoarthritis was observed. Conclusion: The biomaterial enhanced the regeneration process, having an osteoconductive effect during one month postoperative. The preliminary results of this study are promising and gold-nanoparticle biomaterial might be a viable alternative to enhance bone healing after tibial osteotomies to correct cranial cruciate deficient stifle in dogs.
- Subjects
GOLD nanoparticles; BIOMATERIALS; BIOACTIVE glasses; NEOVASCULARIZATION; CRUCIATE ligaments
- Publication
Romanian Journal of Veterinary Medicine & Pharmacology, 2021, Vol 6, Issue 5, p218
- ISSN
2537-4095
- Publication type
Article