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- Title
Composition, Isomer-specific Occurrences, Environmental Fate and Toxicity of Nonylphenols: A Review.
- Authors
Yang Yan; Gao Yuan; Ma Shengtao; Gong Jian; Yu Yingxin
- Abstract
Nonylphenols (NPs) is a toxic xenobiotic compound, which is identified as an environmental endocrine disruptor. Due to its lipophilicity, NPs can easily sorb onto soils and sediments, and persist in the environment for long time. NPs accumulate in various organs and pose toxic effects on organisms. It has been listed as new pollutant under "China's 14th Five-Year Plan", with strict usage prohibition. Theoretically, technical nonylphenol consists of a mixture of 211 possible constitutional isomers with a varied and undefined degree of branching in the alkyl group, among them about 50 -80 individual isomers have been identified in technical mixtures. There is sufficient scientific evidence that the toxicological effects (estrogenic activity), as well as the environmental behavior (degradation and accumulation) of isomers can vary. Therefore, it is necessary to consider the nonylphenol problem from an isomer-specific viewpoint in environmental, exposure, and health studies, which can serve as a fundament for its accurate assessment and prediction of potential health risks. In the present review, the recent advancements and future trends on the isomer composition, isomer-specific occurrences, environmental fate, and toxicity of nonylphenols were summarized. The perspectives and challenges are identified for future studies.
- Subjects
CHINA; NONYLPHENOL; XENOBIOTICS; POISONS; ENDOCRINE disruptors; ALKYL group; ISOMERS; POLLUTANTS; LIPOPHILICITY
- Publication
Asian Journals of Ecotoxicology, 2023, Vol 18, Issue 1, p206
- ISSN
1673-5897
- Publication type
Article
- DOI
10.7524/AJE.1673-5897.20220214002