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- Title
结核病实验室诊断技术研究进展.
- Authors
李忠奇; 吴冰心; 刘巧; 计叶; 王建明
- Abstract
Tuberculosis is a common chronic infectious disease caused by Mycobacterium tuberculosis (M. tb) infection, of which pulmonary tuberculosis is the most common. At present, tuberculosis ranks among the top ten leading causes of death in the world and is the top killer due to a single infections agent, causing serious public health problems around the world. In 2017, there were about 10 million new tuberculosis cases worldwide, and approximately 1.57 million people died of tuberculosis. China is one of the countries with high burden of tuberculosis, with the annual number of patients only less than India, ranking second in the world. It is estimated that about a quarter of the global population is infected with Mycobacterium tuberculosis and is at risk of progressing to active tuberculosis. Tuberculosis patients are the main source of infection. Therefore, accurate diagnosis and treatment of tuberculosis patients at an early stage is of great significance for the prevention and control of tuberculosis. This article reviews the research progress of tuberculosis laboratory diagnostic techniques from three aspects of bacteriology, immunology and molecular biology, and introduces its basic principles and application prospects, aiming to provide reference for the clinical diagnosis of tuberculosis.
- Publication
China Tropical Medicine, 2020, Vol 20, Issue 4, p381
- ISSN
1009-9727
- Publication type
Article
- DOI
10.13604/j.cnki.46-1064/r.2020.04.19