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- Title
Postoperative Nausea & Vomiting (PONV) in Emergency Craniotomy and its Treatment with Ondansetron.
- Authors
Aurang Zeb; Ahmed Zeb; Zahid Ullah Khan; Rahman Ullah Jan; Parhaizgar Khan
- Abstract
Objective: The objective of this study was to evaluate the effectiveness of ondansetron in the treatment of postoperative nausea and vomiting (PONV)in emergency craniotomies. Methods: It was a prospective cross-sectional study of nine months duration that was conducted in the Anesthesia and Neurosurgery departments in two tertiary care hospitals, Peshawar from June 2019 to March 2020. This study was conducted on one hundred and thirty one (131)patients of head trauma in whom emergency craniotomy was required. Data of patients were collected and analyzed through SPSS version 22 software. Results: One hundred and thirty one (131) patients of head trauma were included who underwent craniotomy under GA. Only forty four (33.58%) patients were observed to develop nausea and vomiting. Among these patients, twelve (27.3%) were males and 32(72.7%) were females. All these patients were given ondansetron intravenously. In 39 (88.6%) patients, PONV was completely controlled, and only five (11.4%) patients required other antiemetic drugs in combination with ondansetron for complete remedy. Conclusion: Mortality and morbidity from PONV have markedly decreased in recent years because of improved general anesthesia drugs, early recognition of risk factors, and availability of better antiemetic drugs. Ondansetron is a potent antiemetic drug in the prevention and treatment of PONV in emergency craniotomy under general anesthesia in head trauma patients.
- Subjects
PESHAWAR (Pakistan); POSTOPERATIVE nausea &; vomiting; ONDANSETRON; CRANIOTOMY; GENERAL anesthesia; ANTIEMETICS
- Publication
Ophthalmology Update, 2021, Vol 19, Issue 1, p28
- ISSN
1993-2863
- Publication type
Article