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- Title
Two-mAb cocktail protects macaques against the Makona variant of Ebola virus.
- Authors
Xiangguo Qiu; Audet, Jonathan; Ming Lv; Shihua He; Wong, Gary; Haiyan Wei; Longlong Luo; Fernando, Lisa; Kroeker, Andrea; Bovendo, Hugues Fausther; Bello, Alexander; Feng Li; Pei Ye; Jacobs, Michael; Ippolito, Giuseppe; Saphire, Erica Ollmann; Shengli Bi; Beifen Shen; Gao, George F.; Zeitlin, Larry
- Abstract
The article presents research on the protection of macaques against Ebola virus' (EBOV) Makona variant through monoclonal antibody cocktail. Topics discussed include the outbreak of EBOV in West Africa, the formulation of Zmapp, the human who receive this formulation, and the emergence of pan-ebolavirus cocktail.
- Subjects
MACAQUES; EBOLA virus disease prevention; TREATMENT of Ebola virus diseases; THERAPEUTIC use of monoclonal antibodies; MONOCLONAL antibodies; HEALTH; PHYSIOLOGY
- Publication
Science Translational Medicine, 2016, Vol 8, Issue 329, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aad9875