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- Title
Study some immunological parameters for Salmonella Typhi patients in Hilla city.
- Authors
Alsaffar, Marwa Fadhil; Haleem, Zahraa; Hussian, Mohammed Naser
- Abstract
Background: Salmonella spp. are creatures which might discover likewise normal commensals in the gastrointestinal tracts of man also animals or alternately result in malady that reaches from self-set looseness of the bowels. Salmonella enterica serotype Typhi (Salmonella Typhi) is responsible for a potentially fatal multisystemic illness, these known as typhoid fever or enteric fever. Materials and Methods: Subjects for this study included 40 patients with typhoid fever. Forty blood samples were collected from patients with typhoid fever and clinically diagnosed by doctors based on clinical symptoms of high fever for at least 2 days and severe headache with nausea, abdominal pain, and joints, include 30 females and 10 males with age 10-40 years, the control group study included 15 people apparently healthy that included nine males and six females with age average 20-30 years. Results: Patients of typhoid were divided by age into group, the age group (11-20) was the first age group, the disease rate was 25%, while the second age group (21-30), the disease rate was 55%, was the highest, and the third age group (31-40), the disease rate was 20%. Results of the distribution of study group by gender showed infection that appears in both sexes, with a significant association between the study groups and sex patients of typhoid disease which was more in female. Bacterial growth on growth media after incubation of the plates for 24-48 h showed that the bacterial colonies growing on the growth media were as follows: Transparent with a black center, colorless or pale pink. While microscopic examination, Salmonella, Gram stained bacteria, are characterized by Gram-negative rod cells. The results of the measurement of the concentration of the C-reactive protein showed an increase in the concentration of the age group. The distribution of typhoid patients immunoglobulin (IgM and IgG) measured by rapid cassette, IgM was highest among patients with typhoid (95%), while IgG was 45% and IgM and IgG were among patients (40%). Conclusion: Typhoid fever disease is more common among females than males. Patients with typhoid fever have elevated levels CRP.
- Subjects
TYPHOID fever; SALMONELLA typhi; SALMONELLA enterica serovar Typhi; IMMUNOGLOBULIN M; BACTERIAL colonies; LUMBAR pain; HUMAN-animal relationships; GRAM'S stain
- Publication
Drug Invention Today, 2020, Vol 14, Issue 2, p330
- ISSN
0975-7619
- Publication type
Article