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- Title
A review on association of serum homocysteine in diabetic neuropathy.
- Authors
Rujaswini, T.; Praveen, D.; Chowdary, P. Ranadheer; Aanandhi, M. Vijey; Shanmugasundaram, P.
- Abstract
Diabetes is a disease in which blood glucose or blood sugar levels are too high. Diabetic neuropathy is a type of nerve damage that can occur with diabetes. Symptoms such as pain, tingling, or numbness in the hands, arms, feet, and legs were noted in diabetic neuropathy patients. Roughly, 50% patients with diabetes suffer from diabetic neuropathy. Homocysteine is a nonprotein forming sulfur amino acid. Homocysteine is a common amino acid in blood. Homocysteine is biosynthesized from methionine. Homocysteine levels are typically higher in men than women and increase with age. Elevated homocysteine levels can cause increased inflammation, irritation of the blood vessels, heart disease, neurological troubles, etc. Homocysteine levels are checked through blood tests. Homocysteine is a sensitive biomarker for both folate deficiency and cardiovascular disease. Hyperhomocysteinemia was an independent risk factor for the occurrence of diabetic neuropathy.
- Subjects
TREATMENT of diabetic neuropathies; BLOOD serum analysis; HOMOCYSTEINE; BLOOD sugar measurement; PHARMACODYNAMICS
- Publication
Drug Invention Today, 2018, Vol 10, Issue 2, p154
- ISSN
0975-7619
- Publication type
Article