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- Title
SYNTHESIS AND STRUCTURE OF VANILLIN AZOMETHINES.
- Authors
Konstantinović, Sandra S.; Konstantinović, Budimir V.; Jovanović, Jasmina M.
- Abstract
Vanillin is most prominent as the principal flavor and aroma compound in vanilla. Vanillin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals. The two intermediates, assigned as intermediates I and II, were prepared by using vanillin and 1-butylbromide or 2-chloroacetic acid, respectively. The condensation of intermediates with 2,3- -diaminopyridine gave azomethines. Their structure was established by using elemental microanalysis, as well as UV/Vis, FTIR and 1H-NMR spectra. Synthesized compounds were tested for their antifungal activity against Candida albicans, Candida lipolytica and Sacharomyces cerevisiae.
- Subjects
VANILLIN; VANILLA; CHLOROACETIC acids; CANDIDA; SACCHAROMYCES cerevisiae; ANTIFUNGAL agents; ORGANIC synthesis; MICROCHEMISTRY
- Publication
Chemical Industry & Chemical Engineering Quarterly, 2009, Vol 15, Issue 4, p279
- ISSN
1451-9372
- Publication type
Article
- DOI
10.2298/CICEQ0904279K