Pediatric vesicoureteral reflux is recognized in children whose ureterovesical valve is incompetent, resulting in flow of urine from the kidney to the bladder and back to the kidney. It is a disease process with a rapidly changing management paradigm; more research is being done to determine the long-term outcomes for those affected in both childhood and adulthood. This article will provide a brief overview of current management and discuss the role of the advanced practice registered nurse with families.