We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Treatment of 11 dogs with meningoencephalomyelitis of unknown origin with a combination of prednisolone and cytosine arabinoside.
- Authors
Menaut, P.; Landart, J.; Behr, S.; Lanore, D.; Trumel, C.
- Abstract
The records of 11 dogs with evidence of meningoencephalomyelitis of unknown origin were reviewed. Two of them had had a focal form of the disease and the other nine a disseminated form. The forebrain was involved in five of the nine dogs with disseminated disease, the brainstem in all nine and the cerebellum in one. They had been treated with courses of cytosine arabinoside every three weeks and immunosuppressive doses of presnisolone. Their response to the treatment, in terms of quality of life, was judged by their owners and referring veterinarians to have been excellent in five and poor in one; their survival times ranged from 78 days to more than 603 days. The cumulative probability of survival at two years was 58-4 percent. No signs of myselosuppression or other side effects associated with cytosine arabinoside were observed.
- Subjects
DOG diseases; ENCEPHALOMYELITIS; BRAIN stem; DRUG side effects; VETERINARY drugs
- Publication
Veterinary Record: Journal of the British Veterinary Association, 2008, Vol 162, Issue 8, p241
- ISSN
0042-4900
- Publication type
Article
- DOI
10.1136/vr.162.8.241