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- Title
Prognostic Value of Quantitative p63 Immunostaining in Adenoid Cystic Carcinoma of Salivary Gland Assessed by Computerized Image Analysis.
- Authors
Ramer, Naomi; HaiShan Wu; Sabo, Edmond; Ramer, Yael; Emanuel, Patrick; Orta, Lurmag; Burstein, David E.
- Abstract
The article presents a study which explores role of p63 immunodetection in the prognosis of adenoid cystic carcinoma (ACC) of salivary gland. It states that an image analyzing algorithm was developed using conditional morphological operations to establish precisely the proportions of negatively and positively stained tumor cells. The results show that a cutoff of 35% of tumor cells with p63 positivity distinguished patients with morbidity and mortality from individuals with long-term survival.
- Subjects
ADENOID cystic carcinoma; SALIVARY gland diseases; IMAGE analysis; PROGNOSIS; HISTOPATHOLOGY; CANCER cell physiology
- Publication
Cancer (0008543X), 2010, Vol 116, Issue 1, p77
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.24657