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- Title
The genetics of health.
- Authors
Nadeau, Joseph H.; Topol, Eric J.
- Abstract
Recent experience with several high-profile drugs demonstrates the great challenges in developing effective and safe therapeutics. A complementary approach to the popular paradigm of disease genetics is based on inherited factors that reduce the incidence and severity of disease among individuals who are genetically predisposed to disease. We propose testing specifically for modifier genes and protective alleles among at-risk individuals and studying the efficacy of therapeutics based on the genetics of health.
- Subjects
GENETIC research; HEALTH; HOMEOSTASIS; PHYSICAL fitness &; genetics; IMMUNOMODULATORS
- Publication
Nature Genetics, 2006, Vol 38, Issue 10, p1095
- ISSN
1061-4036
- Publication type
Article
- DOI
10.1038/ng1006-1095