We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and X-ray Structural Analysis of the Ruthenium(III) Complex Na[trans-RuCl<sub>4</sub>(DMSO) (PyrDiaz)], the Diazene Derivative of Antitumor NAMI-Pyr.
- Authors
Vajs, Jure; Pevec, Andrej; Gazvoda, Martin; Urankar, Damijana; Goreshnik, Evgeny; Polanc, Slovenko; Košmrlj, Janez
- Abstract
Novel tetrachloridoruthenium(III) complex Na[trans-RuCl4(DMSO)(PyrDiaz)] (3) with pyridine-tethered diazenedicarboxamide PyrDiaz ligand (PyrDiaz = N1-(4-isopropylphenyl)-N2-(pyridin-2-ylmethyl)diazene-1,2-dicarboxamide) was synthesized by direct coupling of PyrDiaz with sodium trans-bis(dimethyl sulfoxide)tetrachloridoruthenate(III) (Na-[trans-Ru(DMSO)2Cl4]). Compound 3 is the analogue of the antimetastatic Ru(III) complex NAMI-A and NAMI-Pyr. Single crystal X-ray diffraction analysis revealed that the compound 3 is a polymeric complex with the ruthenium and sodium centres.
- Subjects
ANTINEOPLASTIC agents; CANCER cells; CANCER treatment; RUTHENIUM catalysts; DRUG efficacy
- Publication
Acta Chimica Slovenica, 2017, Vol 64, Issue 4, p763
- ISSN
1318-0207
- Publication type
Article
- DOI
10.17344/acsi.2017.3844