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- Title
Progressive retinal vessel malformation in a premature infant with Sturge-Weber syndrome: a case report and a literature review of ocular manifestations in Sturge-Weber syndrome.
- Authors
Zhengping Hu; Jian Cao; Eun Young Choi; Yun Li; Hu, Zhengping; Cao, Jian; Choi, Eun Young; Li, Yun
- Abstract
<bold>Background: </bold>Sturge-Weber syndrome is a disorder marked by a distinctive facial capillary malformation, neurological abnormalities, and ocular abnormalities such as glaucoma and choroidal hemangioma.<bold>Case Presentation: </bold>We report a case of progressively formed retinal vessel malformation in a premature male infant with Sturge-Weber syndrome and retinopathy of prematurity, after treatment with intravitreal anti-vascular endothelial growth factor (VEGF). The baby was born at 30 weeks gestation with a nevus flammeus involving his left eyelids and maxillary area. On postmenstrual age week 39, he received intravitreal anti-VEGF. Diffuse choroidal hemangioma became evident at 40 weeks, with the classic "tomato catsup fundus" appearance. These clinical findings characterized Sturge-weber syndrome. He presented with posterior retinal vessel tortuosity and vein-to-vein anastomoses at 44 weeks.<bold>Conclusion: </bold>This is a rare case of documented progression of retinal vessel malformations in a patient with Sturge-Weber syndrome and retinopathy of prematurity.
- Subjects
STURGE-Weber syndrome; RETINAL blood vessels; PREMATURE infants; OCULAR manifestations of general diseases; ENDOTHELIAL growth factors; CHOROID diseases; DIABETIC retinopathy
- Publication
BMC Ophthalmology, 2021, Vol 21, Issue 1, p1
- ISSN
1471-2415
- Publication type
journal article
- DOI
10.1186/s12886-021-01815-8