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- Title
High Incidence of Respiratory Syncytial Virus in Children with Community-Acquired Pneumonia from a City in the Brazilian Pre-Amazon Region.
- Authors
Fontes, Valéria; Ferreira, Hivylla; Ribeiro, Marilene; Pinheiro, Aruanã; Maramaldo, Carlos; Pereira, Eduardo; Batista, Luís; Júnior, Antonio; Lobato, Luis; Silva, Fabiano; Sousa, Luis; Lima, Washington; Lima, Claudia; Soczek, Suzany; Carvalho, Rafael; Santos, Mirleide; Fernandes, Elizabeth; Sousa, Eduardo; Neto, Lidio
- Abstract
Introduction: Although fewer children have been affected by the severe form of the coronavirus disease 2019 (COVID-19), community-acquired pneumonia (CAP) continues to be the leading global cause of child hospitalizations and deaths. Aim: This study investigated the incidence of respiratory syncytial virus (RSV) as well its subtypes (RSV A and B), adenovirus (ADV), rhinovirus (HRV), metapneumovirus (HMPV), coronavirus (NL63, OC43, 229E and HKU1), parainfluenza virus subtypes (PI1, PI2 and PI3), bocavirus and influenza A and B viruses (FluA and FluB) in children diagnosed with CAP during the COVID-19 pandemic. Methods: A total of 200 children with clinically confirmed CAP were initially recruited, of whom 107 had negative qPCR results for SARS-CoV-2 and were included in this study. Viral subtypes were identified using a real-time polymerase chain reaction in the nasopharyngeal swab samples. Results: Viruses were identified in 69.2% of the patients. RSV infections were the most frequently identified (65.4%), with type RSV B being the most prevalent (63.5%). In addition, HCoV 229E and HRV were detected in 6.5% and 3.7% of the patients, respectively. RSV type B was associated with severe acute respiratory infection (ARI) and a younger age (less than 24 months). Conclusions: New strategies for preventing and treating viral respiratory infections, particularly RSV infections, are necessary.
- Subjects
RESPIRATORY syncytial virus; COVID-19; RESPIRATORY syncytial virus infections; COMMUNITY-acquired pneumonia; COVID-19 pandemic; VIRUS diseases; COMMUNITY gardens; PLANT viruses
- Publication
Viruses (1999-4915), 2023, Vol 15, Issue 6, p1306
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v15061306