We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
New Triterpenoids and Anti-Inflammatory Constituents from Glinus oppositifolius.
- Authors
Chen, Jih-Jung; Yang, Chang-Syun; Chen, Yu-Hui; Chao, Che-Yi; Chen, Yu-Chang; Kuo, Yeuh-Hsiung
- Abstract
Three new triterpenoids—spergulagenin B (1), spergulagenin C (2), and spergulagenin D (3)—were isolated from the aerial part of Glinus oppositifolius, along with 17 known compounds (4–20). The structures of these new compounds were identified by spectroscopic and MS analyses. Compounds 3, 5, 19, and 20 were evaluated for inhibition of nitric oxide production in LPS-stimulated RAW 264.7 cells with IC50 values of 17.03, 18.21, 16.30, and 12.64 μM, respectively. Compounds 3, 5, and 20 exhibited inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 cells with IC50 values of 18.35 ± 1.34, 17.56 ± 1.41, and 14.27 ± 1.29 μM, respectively.
- Subjects
TRITERPENOIDS; NITRIC oxide; QUINAZOLINONES
- Publication
Molecules, 2023, Vol 28, Issue 7, p2903
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules28072903