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- Title
Human CD14 mediates recognition and phagocytosis of apoptotic cells.
- Authors
Devitt, Andrew; Moffatt, Odette D.; Raykundalia, Chandra; Capra, J. Donald; Simmons, David L.; Gregory, Christopher D.
- Abstract
Presents research which showed that apoptotic cells interact with the glycoprotein CD14, triggering phagocytosis of the apoptotic cells. CD14 also acting as a receptor; Recognition and clearance of apoptotic cells by CD14; Effects of overstimulation of CD14; Criteria for interaction of apoptotic cells with CD14; Mediation of apoptotic cell clearance; Implications of results.
- Subjects
APOPTOSIS; GLYCOPROTEINS; PHAGOCYTOSIS; MOLECULES; PHYSIOLOGY
- Publication
Nature, 1998, Vol 392, Issue 6675, p505
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/33169