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- Title
Clinico-Pathological Evaluation of Babesia gibsoni Associated Renal Failure in Dogs.
- Authors
Vidhya, Munagala Sree; Chandrasekar, M.; Arunkumar, S.; Subapriya, S.; Sathish, G.
- Abstract
The aim of the current study was to assess clinical, haematological, and biochemical alterations in dogs infected with Babesia gibsoni, specifically associated with renal complications. Blood samples were obtained from 44 dogs exhibiting symptoms such as fever, lymph node enlargement, and reduced urine output. Babesia piroplasms were detected in 5 cases through blood smear examination, while PCR confirmed 10 positive cases. The dogs that were found positive for B. gibsoni underwent a comprehensive haematological and biochemical analysis to assess the severity of their condition. The primary haematological abnormalities observed were anaemia and thrombocytopenia. Furthermore, the serum biochemical analysis revealed elevated levels of BUN and creatinine, indicating renal insufficiency. Post-mortem examination revealed grossly a capsule firmly adhered to the kidney and during histological examination there was renal tubular dilatation and presence of renal fibrosis. In the chronic stage of the disease, despite the absence of antigen replication within the host's body, the initiated inflammatory response can result in damage to multiple body systems. Therefore, it is of utmost importance to assess the disease's advancement and the overall condition of the animal.
- Subjects
KIDNEY failure; AUTOPSY; BABESIA; DOGS; BLOOD testing; RENAL tubular transport disorders
- Publication
Indian Journal of Veterinary Sciences & Biotechnology, 2024, Vol 20, Issue 3, p77
- ISSN
2394-0247
- Publication type
Article