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- Title
Niclosamide as a promising antibiofilm agent.
- Authors
Zhurina, M.; Gannesen, A.; Mart'yanov, S.; Teteneva, N.; Shtratnikova, V.; Plakunov, V.
- Abstract
Search for inexpensive efficient compounds with antibiofilm activity, which could be applied both for treatment of biofilm-associated infections and in other cases requiring biofilm elimination, is presently of importance. For this purpose we chose niclosamide. Niclosamide is a widespread and available anthelmintic drug, which was also recently shown to suppress bacterial growth. High antibiofilm activity of niclosamide against a range of gram-positive bacteria isolated from different ecological niches was shown. According to our results, niclosamide may be a promising component of composite antibiofilm preparations.
- Subjects
BIOFILMS; ANTHELMINTICS; BACTERIAL growth prevention; GRAM-positive bacteria; MICROORGANISMS
- Publication
Microbiology (00262617), 2017, Vol 86, Issue 4, p455
- ISSN
0026-2617
- Publication type
Article
- DOI
10.1134/S0026261717040154