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- Title
High-throughput Multiplexing Gas Chromatography.
- Authors
Trapp, Oliver
- Abstract
The throughput of conventional separation systems is typically limited by the last eluting component of a mixture. In many applications most of the time is spent recording detector noise. A similar problem was encountered in the development of early continuous wave spectrometers, which was overcome by the introduction of transforms, such at the Fourier or Hadamard transforms. This article describes the use of information technology based on pseudo-random injection sequences derived from Hadamard matrices to perform rapid sample injections to increase the number of samples that can be analysed. This approach, called high-throughput multiplexing gas chromatography (htMPGC), offers a novel way to enhance the overall duty cycle, improve signal-to-noise ratio (SIN) and, ultimately, achieve extraordinarily high sample throughputs.
- Subjects
GAS chromatography; SIGNAL-to-noise ratio; HADAMARD matrices; INFORMATION technology; FOURIER transforms
- Publication
LC-GC Europe, 2011, Vol 24, Issue 4, p172
- ISSN
1471-6577
- Publication type
Article