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- Title
Cost-effectiveness analysis of sacral nerve stimulation as treatment for severe irritable bowel syndrome.
- Authors
Tipsmark, L. S.; Fassov, J.; Lundby, L.; Laurberg, S.; Ehlers, L.; Krogh, K.
- Abstract
Aim Early results from sacral nerve stimulation (SNS) for severe irritable bowel syndrome (IBS) are promising but estimates of cost-effectiveness are lacking. Our object was to perform a cost-effectiveness analysis for SNS as an alternative to no treatment of IBS. Method This retrospective analysis was based on the results from a randomized controlled crossover study with a cost-utility analysis performed on patient-level data and modelling of censored data over a projected period of time of up to 20 years. The analysis was conducted on an intention-to-treat approach. For estimation of the uncertainty of the incremental cost-effectiveness ratio a bias corrected bootstrap analysis was performed. Results Cost-effectiveness was not reached for 4 years after permanent implantation (£31 270 per quality-adjusted life years), which was the upper limit for patient follow-up, but our data imply a cost-effectiveness from a 7-year perspective onwards. Conclusion The study indicates the SNS treatment for IBS is cost effective from a 7-year perspective onwards.
- Subjects
COST effectiveness; SACRAL nerves; IRRITABLE colon treatment; NEURAL stimulation; RANDOMIZED controlled trials; CROSSOVER trials; QUALITY of life
- Publication
Colorectal Disease, 2016, Vol 18, Issue 1, pO30
- ISSN
1462-8910
- Publication type
Article
- DOI
10.1111/codi.13149