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- Title
Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma.
- Authors
Kubasch, Anne Sophie; Franke, Georg-Nikolaus; Aldaoud, Ali; Weibl, Konstantin; Jentzsch, Madlen; Sabri, Osama; Horny, Hans-Peter; Fend, Falko; Behre, Gerhard; Platzbecker, Uwe; Vucinic, Vladan
- Abstract
Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and failure of conventional chemotherapies. Our here presented first report about successful allogeneic hematopoietic stem cell transplantation leading to remission in a case of tonsillar MCS represents a promising potential curative treatment option for this rare and often fatal disease.
- Subjects
HEMATOPOIETIC stem cell transplantation; MAST cells; MAST cell disease; SARCOMA
- Publication
Frontiers in Oncology, 2020, p1
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2020.00219