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- Title
Store-Independent Calcium Entry and Related Signaling Pathways in Breast Cancer.
- Authors
Chamlali, Mohamed; Rodat-Despoix, Lise; Ouadid-Ahidouch, Halima
- Abstract
Known as a key effector in breast cancer (BC) progression, calcium (Ca2+) is tightly regulated to maintain the desired concentration to fine-tune cell functions. Ca2+ channels are the main actors among Ca2+ transporters that control the intracellular Ca2+ concentration in cells. It is well known that the basal Ca2+ concentration is regulated by both store-dependent and independent Ca2+ channels in BC development and progression. However, most of the literature has reported the role of store-dependent Ca2+ entry, and only a few studies are focusing on store-independent Ca2+ entry (SICE). In this review, we aim to summarize all findings on SICE in the BC progression field.
- Subjects
TRP channels; BREAST cancer; CALCIUM; CANCER cells
- Publication
Genes, 2021, Vol 12, Issue 7, p994
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes12070994