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- Title
SYNTHESIS OF PYRAZOLINE VIA BIOCATALYTIC CYCLOCONDENSATION WITH SACCHAROMYCES CEREVISIAE.
- Authors
Mandal, Suraj; Khalilullah, Habibullah; Rangavitala P.; Agrawal, Ankur; Kumar, Avinash; Singh, Damini
- Abstract
Saccharomyces cerevisiae was utilized in the underlying biocatalytic cyclocondensation interaction to combine pyrazoline. Utilizing S. cerevisiae's enzymatic capacities, the procedure produces pyrazoline, a critical heterocyclic synthetic with a large number of purposes in materials science and drugs. This strategy offers benefits over customary courses for the synthesis of substances, for example, milder response conditions, further developed selectivity, and lower natural impact, by employing biocatalysts that are both practical and harmless to the biological system. The potential purposes of the created pyrazoline compounds are investigated alongside the synthesis course and reaction upgrade methods. This work underlines the potential of S. cerevisiae as an adaptable biocatalyst in synthetic chemistry and the captivating job that biocatalysis plays in the synthesis of perplexing regular compounds. An effortless, effective, and harmless to the ecosystem technique for combining pyrazoline has been created utilizing the cyclocondensation of chalcones and hydrazine hydrate with the surprisingly economical impetus, mixture puncher's yeast (Saccharomyces cerevisiae). A moderate to high return of 3,5-diphenyl pyrazolines is delivered during synthesis. Alongside conquering the weaknesses of prior pyrazoline synthesis strategies, the procedure offers a more viable method for creating 3,5-diphenyl pyrazoline derivatives.
- Subjects
SACCHAROMYCES cerevisiae; CONDITIONED response; MATERIALS science; BIOLOGICAL systems; ENZYMES
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 6, p967
- ISSN
0975-3583
- Publication type
Article