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- Title
Determination of the prevalence of antimicrobial-resistant infection among patients attending a tertiary care in out patient setting.
- Authors
Gera, Rajesh; Singh Brar, Phool Kanwar
- Abstract
Background: It is becoming more frequent for organisms of different generations to acquire resistance to widely-used antibiotics. Due to a lack of monitoring of antimicrobial resistance (AMR), India remains in the dark about the true state of AMR throughout the country. Aim: To determine the prevalence of antimicrobial-resistant infection among patients attending the tertiary care OPD. Material and Methods: After obtaining approval from the relevant authorities, the research was conducted inside the internal medicine department. Included in the analysis were the antibiotic susceptibility test results of clinical specimens such as urine, blood, vaginal swabs, pus, samples from indwelling urinary catheters, pleural fluid, stool, wound swabs, abscess swabs, sputum, aspirates, and urethral swabs collected during the study period. Results: One hundred patients were analyzed in this research. E. coli was the most common kind of bacterium. Microorganisms such as E. coli (20%), S. aureus (30%), K. pneumoniae (30%), S. pneumoniae (10%), and other bacteria (10%). The ampicillin (100%) and amoxicillin/clavulanate (83.33%) showed substantial resistance rates among E. coli isolates. There was a significant amount of resistance to the oral cephalosporins cefotaxime (70%) and cefoxitin (93.33%) among the isolates. There was also a significant proportion of resistance to various antibacterial drugs, including ciprofloxacin (50 percent), gentamicin (50 percent), trimethoprim-sulfamethoxazole (73.33 percent), and imipenem (13.3 percent). The resistance rates of Klebsiella pneumoniae isolates were greater than those of E. coli. Antibiotics against E. coli that have a high resistance rate include: amoxicillin/clavulanate (65%), cefotaxime (50%), cefoxitin (55%), ciprofloxacin (30%), gentamicin (75%), tetracycline (75%), and trimethoprim-sulfamethoxazole (75%). However, resistance to carbapenem was somewhat more in case of K. pneumonia than E.Coli Conclusion: Considering the widespread antibiotic resistance shown in E. coli, we came to this conclusion. This could complicate treatment options for community-acquired infections.
- Subjects
INDIA; ESCHERICHIA coli; URINARY tract infections; MICROBIAL sensitivity tests; PLEURAL effusions; TERTIARY care; URINARY catheters; COMMUNITY-acquired infections
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2022, Vol 13`, Issue 8, p795
- ISSN
0975-3583
- Publication type
Article