We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Association between Serum Uric Acid Levels and Diabetes Mellitus.
- Authors
Bandaru, Pavani; Shankar, Anoop
- Abstract
Serum uric acid has been shown to be associated with cardiovascular disease, hypertension, and chronic kidney disease in previous studies. However, few studies have examined the association between serum uric acid and diabetes mellitus and their findings are not consistent. Therefore, we examined the association between serum uric acid levels and diabetes mellitus in participants from the third National Health and Nutrition Examination Survey (n =18, 825, 52.5% women). Serum uric acid levels were categorized into quartiles. Diabetes mellitus was defined as fasting glucose ≥126 mg/dL, nonfasting glucose ≥200 mg/dL, or use of oral hypoglycemic medication or insulin (n = 395). In multivariable logistic regression models, we found that higher serum uric acid levels were inversely associated with diabetes mellitus after adjusting for age, sex, race/ethnicity, education, smoking, alcohol intake, body mass index, hypertension, and serum cholesterol. Compared to quartile of serum uric acid, the odds ratio (95% confidence interval) of diabetes mellitus was 0.48 (0.35-0.66; P trend < 0.0001). The results were consistent in subgroup analysis by gender and hypertension status. Higher serumuric acid levels were inversely associated with diabetes mellitus in a representative sample of US adults.
- Subjects
DIABETES; SERUM; URIC acid; MULTIPLE regression analysis; BODY mass index
- Publication
International Journal of Endocrinology, 2011, p1
- ISSN
1687-8337
- Publication type
Article
- DOI
10.1155/2011/604715