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- Title
Tracing the potential of lung progenitors.
- Authors
Mahoney, John E; Kim, Carla F
- Abstract
The article presents two studies conducted by W. Zuo and colleagues and A.E. Vaughan describe different populations of distal lung stem or progenitor cells that help in lung repair. Topics discussed include use of transgenic mice expressing tamoxifen-dependent lacZ under the control of the bovine Krt5 promoter, use of genetic lineage tagging approaches to characterize cell population, and failure of marker integrin-Beta4 in isolating lineage-negative epithelial progenitor (LNEP) cell.
- Subjects
VAUGHAN, A. E.; PROGENITOR cells; TAMOXIFEN; PROMOTERS (Genetics)
- Publication
Nature Biotechnology, 2015, Vol 33, Issue 2, p152
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt.3139