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- Title
Validity of bioelectrical impedance analysis to assess fat-free mass in patients with head and neck cancer: An exploratory study.
- Authors
Jager–Wittenaar, Harriët; Dijkstra, Pieter U.; Earthman, Carrie P.; Krijnen, Wim P.; Langendijk, Johannes A.; Laan, Bernard F.A.M.; Pruim, Jan; Roodenburg, Jan L.N.
- Abstract
ABSTRACT: Background The purpose of this study was to validate bioelectrical impedance analysis (BIA) using the Geneva equation for fat-free mass (FFM) in patients with head and neck cancer. Methods In 24 patients with head and neck cancer, agreement between BIA (FFMBIA) and dual energy x-ray absorptiometry (FFMDXA) 1 week before (T0), 1 month (T1), and 4 months (T2) after cancer treatment was analyzed. Results FFMBIA did not differ from FFMDXA (mean difference 0.71 ± 1.9, 0.30 ± 1.9, and 0.02 ± 2.1 kg) at any time point. Only at T0, mean FFM correlated to the difference between FFMDXA and FFMBIA ( r = 0.48; p = .017). Limits of agreement were 3.8, 3.7, and 4.1 kg, respectively. Concordance Correlation Coefficients were 0.98 at all time points. Conclusion BIA may be used to assess FFM with reasonable validity based on mean-level comparisons, but differences between BIA and DXA may vary by about 4 kg in an individual patient. These results require confirmation in a larger sample of patients with head and neck cancer. © 2013 Wiley Periodicals, Inc. Head Neck 36: 585-591, 2014
- Subjects
CANCER patients; CANCER treatment; BIOELECTRIC impedance; ELECTROPHYSIOLOGY; DUAL-energy X-ray absorptiometry
- Publication
Head & Neck, 2014, Vol 36, Issue 4, p585
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.23336