We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Combined Ranibizumab and Subtenon Triamcinolone Injection for Macular Edema Secondary to Branch Retinal Vein Occlusion.
- Authors
ERÇALIK, Yeşim; İMAMOĞLU, Serhat; TÜRKSEVEN KUMRAL, Esra; MELDA YENEREL, Nursal; BARDAK, Handan; BARDAK, Yavuz
- Abstract
Purpose: To evaluate the outcomes of combined intravitreal ranibizumab (IVR) and posterior subtenon triamcinolone acetonide (STTA) injection for the treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods: Nineteen eyes of 19 patients with BRVO and cystoid ME were examined in this retrospective study. Nine eyes were treated with IVR and STTA, and afterwards with pro re nata (PRN) IVR (combined group) and 10 eyes received PRN IVR (control group). The outcome measures were: changes in the central macular thickness (CMT), best corrected visual acuity (BCVA), intraocular pressure (IOP), and number of injections. Results: The mean initial CMT was 541±103µm in the combined and 475±57 µm in the control group (p=0.14). The median baseline BCVA was 1.0 (0.60-1.15) LogMAR in the combined group and 0.75 (0.47-1.07) LogMAR in the control group (p=0.5). In both groups, CMT was significantly reduced and BCVA was significantly improved at the 1st and 3rd months and at the 1st year. In the first 3 months, the combined group received a single dose, whereas the control group was treated with a median number of 2.5 (2-3) injections (p< 0.001). Nevertheless, the number of additional injections after the 1st injection wasn't significant between the groups [combined group: median 3 (1.5-3), control group: median 3 (1.75-4] p=0.34). No IOP elevations or other injection-related complications were encountered. Conclusions: Combined IVR and STTA therapy seems to be comparable to IVR monotherapy in improving both CMT and BCVA in BRVO, with similar additional injection numbers.
- Subjects
RETINAL vein occlusion; RANIBIZUMAB; TRIAMCINOLONE; INTRAOCULAR pressure; TRIAMCINOLONE acetonide
- Publication
Retina-Vitreus/Journal of Retina-Vitreous, 2019, Vol 28, Issue 3, p229
- ISSN
1300-1256
- Publication type
Article