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- Title
Warm autoimmune hemolytic anemia associated with SARS-CoV-2 infection responsive to eculizumab.
- Authors
Gong, Yuemin; Zhang, Xinyu; Chen, Xiaoyu; Yang, Hui; Zhang, Yawen; He, Guangsheng; Li, Jianyong
- Abstract
This letter published in the Annals of Hematology describes three cases of warm autoimmune hemolytic anemia (wAIHA) that occurred after SARS-CoV-2 infection and were successfully treated with eculizumab. The first patient had a history of hemolysis and achieved remission after receiving eculizumab. The second patient experienced a hemolysis flare and responded to eculizumab after other treatments failed. The third patient had Evans' syndrome and achieved a response with eculizumab. This case series suggests that complement modulation with eculizumab may be effective in treating COVID-19-associated wAIHA, but further research is needed.
- Subjects
AUTOIMMUNE hemolytic anemia; SARS-CoV-2; ECULIZUMAB
- Publication
Annals of Hematology, 2024, Vol 103, Issue 3, p1007
- ISSN
0939-5555
- Publication type
Article
- DOI
10.1007/s00277-023-05549-z