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- Title
The impact of serum uric acid on the diagnostic of metabolic syndrome in apparently healthy Brazilian middle-aged men.
- Authors
de Oliveira, Alessandro; Miranda Hermsdorff, Helen Hermana; Guedes Cocate, Paula; Bressan, Josefina; Azevedo Novello, Alexandre; Cardoso dos Santos, Eliziaria; Natali, Antônio José
- Abstract
Background: Hyperuricemia is related to Metabolic- Syndrome (MetS) and cardiovascular diseases, but the use of serum uric acid (UA) to diagnose MetS is currently ignored in clinical practices. Objectives: To examine the impact of serum UA on the diagnostic of MetS and the relationship of serum UA with cardiometabolic risk factors in apparently healthy Brazilian middle-aged men residents in a city of Minas Gerais. Methods: In a cross-sectional analysis, 289 apparently healthy middle-aged men underwent anthropometric, clinical, sociodemographic and blood serum biochemical evaluation. By using receive operating curve the internal cutoff of serum UA was determined (5.25 mg/dL). Results: Subjects with two or more components of MetS exhibited higher serum UA as compared to those with one or none component. The inclusion of serum UA ≥ 5.25mg/dL as an additional component of MetS increased the occurrence of this syndrome by 13%. Subjects with UA ≥ 5.25mg/dL showed high prevalence for MetS and association with its components (central obesity, hypertriglyceridemia, dyslipidemia and hypertension) as well as atherogenic risk. Conclusions: Serum UA has an important impact on the diagnostic of MetS and is related to cardiometabolic risk factors in apparently healthy Brazilian middle-aged men. Its use in clinical practices could aggregate accuracy to diagnose MetS.
- Subjects
BRAZILIANS; URIC acid; METABOLIC syndrome; CARDIOVASCULAR diseases; HYPERURICEMIA; HEALTH
- Publication
Nutrición Hospitalaria, 2014, Vol 30, Issue 3, p562
- ISSN
0212-1611
- Publication type
Article
- DOI
10.3305/nh.2014.30.3.7540