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- Title
Retinal vein and artery occlusion as the first manifestation of primary antiphospholipid syndrome in a pediatric patient.
- Authors
Delgado João, Marina; Vasco Costa, Jorge; Calvão Santos, Gil; Dourado Leite, Ricardo; Guimarães, Sandra
- Abstract
Antiphospholipid syndrome is an acquired autoimmune disease characterized by hypercoagulability associated with recurrent venous and arterial thromboembolism in the presence of antiphospholipid antibodies. Herein, we report a case of rapid sequential retinal vein and artery occlusion as the first manifestation of a primary antiphospholipid syndrome triggered by an acute Mycoplasma infection in a previously healthy 11-year-old patient. On day 1, ophthalmoscopy revealed a central retinal vein occlusion. The patient developed temporal branch retinal artery occlusion the next day. On day 3, a central retinal artery occlusion was observed. Serum lupus anticoagulant, immunoglobulin (Ig) G anticardiolipin, IgG anti-ß2-glycoprotein 1 antibody, and Mycoplasma pneumoniae IgM antibody levels were increased. Thus, retinal vascular occlusions can be the first manifestation of primary antiphospholipid syndrome. Although it may not improve visual prognosis, prompt diagnosis and treatment are essential to avoid further significant morbidity.
- Subjects
RETINAL artery occlusion; RETINAL vein occlusion; MYCOPLASMA pneumoniae infections; ANTIPHOSPHOLIPID syndrome; CHILD patients; SYNDROMES in children; RETINAL artery
- Publication
Arquivos Brasileiros de Oftalmologia, 2024, Vol 87, Issue 2, p1
- ISSN
0004-2749
- Publication type
Article
- DOI
10.5935/0004-2749.2021-0431