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- Title
Use of prophylactic phototherapy for RhD neonatal disease in a referral service.
- Authors
Marques da Silva Robalinho Rodrigues, Joyce; Barbosa Baker Méio, Maria Dalva; Pessoa dos Santos, Maria Cristina; Carioca da Costa, Ana Carolina; Lopes Moreira, Maria Elisabeth
- Abstract
Objective: This study aimed to describe the effect of prophylactic phototherapy in the treatment of infants with Neonatal Hemolytic Disease. Method: A retrospective cohort study was carried out with 199 RhD-positive infants, born to RhD-negative mothers, alloimmunized for RhD antigen, between January 2009 and December 2018. Results: The incidence of exchange transfusions in the study population was 9.5%, with a mean maximum bilirubin value of 11.3 mg % (± 4.3mg %). Bilirubin's maximum peak was achieved with a mean of 119.2 life hours (± 70.6h). Conclusion: The low incidence of exchange transfusion, the extended maximum bilirubin peak for later ages, and the low mean of the maximum bilirubin values may indicate a positive effect of prophylactic phototherapy in the treatment of this disease. Further studies must be carried out to confirm these findings.
- Subjects
NEONATAL diseases; PHOTOTHERAPY; BLOOD transfusion; ERYTHROBLASTOSIS fetalis; THERAPEUTICS
- Publication
Jornal de Pediatria, 2023, Vol 99, Issue 1, p53
- ISSN
0021-7557
- Publication type
Article
- DOI
10.1016/j.jped.2022.04.004