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- Title
Transient Fanconi Syndrome After Treatment with Firocoxib, Cefadroxil, Tramadol, and Famotidine in a Maltese.
- Authors
Ahn, Jin-Ok; Kim, Sang-Min; Song, Woo-Jin; Ryu, Min-Ok; Li, Qiang; Chung, Jin-Young; Youn, Hwa-Young
- Abstract
Fanconi syndrome is a renal proximal tubulopathy characterized by excessive urinary loss of glucose, amino acids, several electrolytes, and bicarbonate. Here, we report the case of transient Fanconi syndrome in a dog following administration of firocoxib, cefadroxil, tramadol, and famotidine. A 10 mo old Maltese was presented with lethargy, anorexia, vomiting, and weight loss. Transient Fanconi syndrome without azotemia was associated with firocoxib, cefadroxil, tramadol, and famotidine treatment. The dog received supportive care including IV fluids, gastroprotectants, and oral nutritional supplements. Two months after initial diagnosis and treatment, the dog showed complete resolution of glucosuria and aminoaciduria. The unique features of Fanconi syndrome in this case emphasize the potential renal tubular toxicity of this widely used multiple-drug combination.
- Subjects
FANCONI syndrome; FAMOTIDINE; NEPHROTOXICOLOGY; H2 receptor antagonists; WEIGHT loss; DOG shows; BICARBONATE ions
- Publication
Journal of the American Animal Hospital Association, 2019, Vol 55, Issue 6, p323
- ISSN
0587-2871
- Publication type
Article
- DOI
10.5326/JAAHA-MS-6786