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- Title
Periacetabular osteotomy to treat hip dysplasia: a systematic review of harms and benefits.
- Authors
Tønning, Lisa U.; O'Brien, Michael; Semciw, Adam; Stewart, Christopher; Kemp, Joanne L.; Mechlenburg, Inger
- Abstract
Introduction: Periacetabular osteotomy (PAO) is often performed in patients with hip dysplasia. The aim of this systematic review and meta-analysis was to evaluate the harms and benefits of PAO in patients with hip dysplasia in studies reporting both adverse events and patient-reported hip pain and function. Materials and methods: A systematic search combing PAO and patient-reported outcomes was performed in the databases MEDLINE, CINAHL, EMBASE, Sports Discuss and PsychINFO. Studies including both harms and benefits defined as adverse events and patient-reported hip pain and function were included. Risk of bias was assessed using The Cochrane Risk of Bias In Non-Randomized Studies – of Interventions. Results: Twenty-nine cohort studies were included, of which six studies included a comparison group. The majority of studies had serious risk of bias and the certainty of evidence was very low. The proportion of adverse events was 4.3 (95% CI 3.7; 4.9) for major adverse events and 14.0 (95% CI 13.0; 15.1) for minor adverse events. Peroneal nerve dysfunction was the most frequent adverse event among the major adverse events, followed by acetabular necrosis and delayed union or non-union. All patient-reported hip pain and function scores improved and exceeded the minimal clinically important differences after PAO. After 5 years, scores were still higher than the preoperative scores. Conclusion: PAO surgery has a 4% risk of major, and 14% risk of minor adverse events and a positive effect on patient-reported hip pain and function among patients with hip dysplasia.
- Subjects
ACETABULUM surgery; DYSPLASIA; OSTEOTOMY; PERONEAL nerve; CINAHL database
- Publication
Archives of Orthopaedic & Trauma Surgery, 2023, Vol 143, Issue 6, p3637
- ISSN
0936-8051
- Publication type
Article
- DOI
10.1007/s00402-022-04627-7