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- Title
Nucleophilic Addition of Oxindole to Pyrrolobenzoxazinetriones.
- Authors
Topanov, P. A.; Mashevskaya, I. V.; Dmitriev, M. V.; Maslivets, A. N.
- Abstract
3-Aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones reacted with oxindole to give in good yields products of addition of the C3 atom of the latter to the C3a atom of the former, 3-aroyl-2-hydroxy-3a(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aH)-diones, that are promising as potential biologically active compounds. The reactions occur under mild conditions in the absence of catalysts or other additives, and isolation of the products requires no chromatographic separation.
- Subjects
BIOACTIVE compounds; INDOLE; BENZOXAZINES
- Publication
Russian Journal of Organic Chemistry, 2021, Vol 57, Issue 1, p126
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S107042802101019X