We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Therapeutic Regimens of Osteoporosis in Bahrain: A Drug Audit.
- Authors
Tayem, Yasin I.; Hassan, Adla B.; Almarabheh, Amer; Ezat, Aayat E.; Ibrahim, Asgad K.; AlAwadhi, Danya A.; Fathalla, Haifa A.; Abdalla, Heba A.; Ghalib, Kanz A.; Naser, Manar S.; Hozayen, Reham F.; Mohamed, Sara J.; Alherz, Walaa A.; Naser, Weqar S.; Alherz, Zahra A.; Mustafa, Zahra S.; Mattar, Mai E.
- Abstract
Objective: We examined the protocol for drug selection and bone mineral density follow up for a sample of osteoporosis patients in Bahrain. Methods: This was a retrospective study. Data was collected from three hospitals in Bahrain over the period 2016-2018. We collected subject's demographic data, osteoporosis drug therapy, and the schedule of dual-energy X-ray absorptiometry (DXA) scan before and after therapy. Results: The number of subjects who were included in this study was 4572 (mean age 59.36 years: 92.5% females, 7.5% males). We found that 41.8% of the patients used osteoporosis medications, whereas the rest were not on any pharmacotherapy (58.2%). The following drugs were used: Vitamin D (82.4%), Calcium (76.6%), Denosumab (14.9%), Bisphosphonate (4.5%) and Tamoxifen (4.3%). Almost all subjects were offered BMD scan before therapy (96.5%), but minority received a follow up after starting medications (17.2%). The follow up scan was performed 2-3 years following therapy in 46.9% of subjects, whereas for the rest, it was requested 1-2 years (31.1%) or 3 years (17.1%) later. Pharmacotherapy was associated with age (p<0.001), female gender (p<0.05) and being postmenopausal (p<0.001). Follow up BMD was positively associated with age (p<0.001), postmenopausal status (p<0.001) and medication use (p<0.001). Conclusions: Osteoporosis patients were undertreated with anti-resorptive drugs and most of them were not offered a follow up DXA scan to assess response to therapy. Protocol for pharmacotherapy and follow up of osteoporosis in Bahrain needs review.
- Subjects
BAHRAIN; DUAL-energy X-ray absorptiometry; OSTEOPOROSIS; BONE density; DRUG therapy; VITAMIN D
- Publication
Bahrain Medical Bulletin, 2023, Vol 45, Issue 3, p1691
- ISSN
1012-8298
- Publication type
Article