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- Title
The Impact of Comorbid Diabetes on Short-Term Postoperative Outcomes in Stage I/II Colon Cancer Patients Undergoing Open Colectomy.
- Authors
Lee, Ko-Chao; Chung, Kuan-Chih; Chen, Hong-Hwa; Cheng, Kung-Chuan; Wu, Kuen-Lin; Song, Ling-Chiao; Hu, Wan-Hsiang
- Abstract
Purpose. This study aimed at evaluating the impact of comorbid diabetes on short-term postoperative outcomes in patients with stage I/II colon cancer after open colectomy. Methods. The data were extracted from the National Inpatient Sample database (2005-2010). Short-term surgical outcomes included in-hospital mortality, postoperative complications, and hospital length of stay. Results. A total of 49,064 stage I/II colon cancer patients undergoing open surgery were included, with a mean age of 70.35 years. Of them, 21.94% had comorbid diabetes. Multivariable analyses revealed that comorbid diabetes was significantly associated with a lower risk of in-hospital mortality and postoperative complications. Compared to patients without diabetes, patients with uncomplicated diabetes had lower percentages of in-hospital mortality and postoperative complications, but patients with complicated diabetes had a higher percentage of postoperative complications. In addition, patients with diabetes only, but not patients with diabetes and hypertension only, had a lower percentage of in-hospital mortality than patients without any comorbidity. Conclusion. The present results suggested the protective effects of uncomplicated diabetes on short-term surgical outcomes in stage I/II colon cancer patients after open colectomy. Further studies are warranted to confirm these unexpected findings and investigate the possible underlying mechanisms.
- Subjects
DIABETES complications; SURGICAL complication risk factors; COLECTOMY; COLON tumors; COMPARATIVE studies; LENGTH of stay in hospitals; HYPERTENSION; MULTIVARIATE analysis; RISK assessment; TUMOR classification; COMORBIDITY; TREATMENT effectiveness; HOSPITAL mortality; DISEASE complications; OLD age
- Publication
BioMed Research International, 2020, p1
- ISSN
2314-6133
- Publication type
Article
- DOI
10.1155/2020/2716395