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- Title
Shifting archetype to nature's hidden gems: from sources, purification to uncover the nutritional potential of bioactive peptides.
- Authors
Manzoor, Madhiya; Mir, Rakeeb Ahmad; Farooq, Asmat; Hami, Ammarah; Pakhtoon, Mohammad Maqbool; Sofi, Sajad Ahmad; Malik, Firdose Ahmad; Hussain, khursheed; Bhat, M. Ashraf; Sofi, Najeebul Rehmen; Pandey, Anamika; Khan, Mohd. Kamran; Hamurcu, Mehmet; Zargar, Sajad Majeed
- Abstract
Contemporary scientific findings revealed that our daily food stuffs are enriched by encrypted bioactive peptides (BPs), evolved by peptide linkage of amino acids or encrypted from the native protein structures. Remarkable to these BPs lies in their potential health benefiting biological activities to serve as nutraceuticals or a lead addition to the development of functional foods. The biological activities of BPs vary depending on the sequence as well as amino acid composition. Existing database records approximately 3000 peptide sequences which possess potential biological activities such as antioxidants, antihypertensive, antithrombotic, anti-adipogenics, anti-microbials, anti-inflammatory, and anti-cancerous. The growing evidences suggest that BPs have very low toxicity, higher accuracy, less tissue accretion, and are easily degraded in the disposed environment. BPs are nowadays evolved as biologically active molecules with potential scope to reduce microbial contamination as well as ward off oxidation of foods, amend diverse range of human diseases to enhance the overall quality of human life. Against the clinical and health perspectives of BPs, this review aimed to elaborate current evolution of nutritional potential of BPs, studies pertaining to overcome limitations with respect to special focus on emerging extraction, protection and delivery tools of BPs. In addition, the nano-delivery mechanism of BP and its clinical significance is detailed. The aim of current review is to augment the research in the field of BPs production, identification, characterisation and to speed up the investigation of the incredible potentials of BPs as potential nutritional and functional food ingredient.
- Subjects
FUNCTIONAL foods; AMINO acid sequence; PEPTIDES; PROTEIN structure; MICROBIAL contamination; AMINO acids
- Publication
3 Biotech, 2023, Vol 13, Issue 7, p1
- ISSN
2190-572X
- Publication type
Article
- DOI
10.1007/s13205-023-03667-z